Tubeless Anesthesia in Preventing Lung Complications in Patients Undergoing Surgery for Early-Stage Lung Cancer

NARecruitingINTERVENTIONAL
Enrollment

224

Participants

Timeline

Start Date

May 25, 2025

Primary Completion Date

May 1, 2026

Study Completion Date

December 3, 2027

Conditions
Lung Cancer Patients
Interventions
PROCEDURE

Tubeless anesthesia

"1. Anesthesia Induction: Implement TCI with propofol and remifentanil; insert a laryngeal mask for SIMV ventilation, and monitor vital signs including IBP and end-tidal CO2.~2. Nerve Blocks: Perform ultrasound-guided paravertebral, pleural surface, and vagus nerve blocks using local anesthetics.~3. Anesthesia Maintenance: Adjust remifentanil for spontaneous breathing; maintain propofol and BIS levels; manage heart rate and blood pressure with fluids and medication as needed, without using inhaled anesthetics.~4. Postoperative Analgesia: Provide PCIA with morphine for pain management."

PROCEDURE

Traditional tracheal intubation

"1. Anesthesia induction using propofol, sufentanil, and rocuronium is performed, with DLT or single-lumen tube insertion at BIS≤60 for single-lung ventilation, maintaining appropriate oxygen and ventilation parameters.~2. Anesthesia is maintained with sevoflurane, propofol, and remifentanil, supplementing rocuronium every 30-40 minutes for muscle relaxation, with BIS maintained at 40-60.~3. Post-surgery, ultrasound-guided thoracic paravertebral block and PCIA are used for analgesia, with extubation following standard recovery procedures."

Trial Locations (1)

350001

RECRUITING

Fujian Medical University Union Hospital, Fuzhou

All Listed Sponsors
lead

Fujian Medical University Union Hospital

OTHER

NCT07024433 - Tubeless Anesthesia in Preventing Lung Complications in Patients Undergoing Surgery for Early-Stage Lung Cancer | Biotech Hunter | Biotech Hunter