Comparison of the Effectiveness of Paracetamol With Ibuprofen or Paracetamol With Metamizole in Treating Pain in Acute Pancreatitis in Children

PHASE4RecruitingINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

June 1, 2027

Study Completion Date

June 1, 2027

Conditions
Pancreatitis, AcutePain, AcutePancreatic DiseasePancreatic DiseasesGastroenterologyPancreatitisPaediatrics
Interventions
OTHER

The initial pain assessment

The initial pain assessment will be carried out according to pain assessment scales in children adapted to the patient's age and cognitive abilities (NRS, FLACC).

DRUG

Drug administration according to protocol (paracetamol + ibuprofen OR paracetamol + metamizol)

"Group A will receive a dose of Paracetamol B. Braun/Paracetamol Kabi intravenously 15 mg/kg body weight (maximum 1000 mg/dose) and Ibuprofen B.Braun/Ibuprofen Kabi intravenously 10 mg/kg body weight (maximum 400 mg/dose).~Group B will receive a dose of Paracetamol B. Braun/Paracetamol Kabi intravenously 15 mg/kg body weight (maximum 1000 mg/dose) and Metamizol-SF/Metamizole Kabi/Pyralgin intravenously 15 mg/kg body weight (maximum 100 mg/dose)."

OTHER

The effectiveness of the treatment

The effectiveness of the treatment will be assessed 60 minutes after the start of the intervention according to pain assessment scales in children adapted to the patient's age and cognitive abilities (NRS, FLACC).

Trial Locations (1)

02-091

RECRUITING

Department of Paediatric Gastroenterology and Nutrition, Warsaw

All Listed Sponsors
lead

Medical University of Warsaw

OTHER