Personalized Timing of Interval Debulking Surgery in Advanced Ovarian Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

126

Participants

Timeline

Start Date

May 22, 2025

Primary Completion Date

December 31, 2028

Study Completion Date

December 31, 2028

Conditions
Ovarian CancerFallopian Tube CancerPrimary Peritoneal Carcinoma
Interventions
DIAGNOSTIC_TEST

KELIM

(i) Patients with KELIM =\>1 will receive radiological assessment and undergo internal debulking surgery if the disease is operable. (ii) Patients with KELIM \<1 will have alternative management, such as addition of bevacizumab or changing to dose-dense chemotherapy, and defer the interval debulking surgery

DRUG

Carboplatin plus Paclitaxel

Neoadjuvant chemotherapy

PROCEDURE

Interval debulking surgery

Interval debulking surgery

Trial Locations (6)

Unknown

NOT_YET_RECRUITING

Sun Yat-sen University Cancer Center, Guangzhou

NOT_YET_RECRUITING

The University of Hong Kong - Shenzhen Hospital, Shenzhen

NOT_YET_RECRUITING

Pamela Youde Nethersole Eastern HospitalPamela Y, Chai Wan

NOT_YET_RECRUITING

Queen Mary Hospital, Department of Clinical Oncology, Hong Kong

RECRUITING

The University of Hong Kong, Department of Obstetrics and Gynaecology, Hong Kong

NOT_YET_RECRUITING

United Christian Hospital, Kwun Tong

All Listed Sponsors
collaborator

Queen Mary Hospital, Hong Kong

OTHER

collaborator

United Christian Hospital

OTHER

collaborator

Pamela Youde Nethersole Eastern Hospital

OTHER

collaborator

The University of Hong Kong-Shenzhen Hospital

OTHER

collaborator

Sun Yat-sen University Cancer Centre

UNKNOWN

lead

The University of Hong Kong

OTHER