750
Participants
Start Date
July 31, 2025
Primary Completion Date
July 31, 2027
Study Completion Date
July 31, 2027
RS ratio
We will evaluate the non-culture, sputum-based assay RS ratio, which measures ongoing Mycobacterium tuberculosis activity by quantifying the abundance of precursor rRNA relative to mature rRNA (an indicator of active rRNA synthesis).
Blood-based host immune response assays
We will evaluate blood-based assays measuring host immune response parameters for predicting mycobacterial activity.
RECRUITING
Kisenyi Health Center, Kampala
RECRUITING
Mulago Outpatient Department, Kampala
NOT_YET_RECRUITING
Hanoi Lung Hospital, Outpatient departments, Hanoi
University of California, Irvine
OTHER
University of Colorado, Denver
OTHER
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
University of California, San Francisco
OTHER