Effects of Saccharomyces Boulardii CNCM I-745 on Antibiotic-Associated Perturbation in Children Treated for Acute Respiratory Infections (RESTORE Study)

PHASE4Not yet recruitingINTERVENTIONAL

Enrollment

100

Participants

Timeline

Start Date

June 10, 2025

Primary Completion Date

June 1, 2026

Study Completion Date

December 31, 2026

Conditions

Antibiotic Associated DiarrheaAcute Otitis MediaACUTE SINUSITIS

Interventions

DRUG

Amoxicillin-Clavulanic acid 600mg - 42.9 mg/ 5 mL oral suspension

Standard treatment (50-90 mg/kg/day for 10 days)

DIETARY_SUPPLEMENT

Saccharomyces boulardii CNCM I-745

Probiotic sachet, twice daily for 10 or 21 days depending on group assignment

Trial Locations (1)

Eskisehir Osmangazi University, Eskişehir

All Listed Sponsors

collaborator

Turkish Pediatric Probiotic Prebiotic and Microbiota Society

UNKNOWN

lead

Eskisehir Osmangazi University

OTHER