Robot-Aided Off-Axis Neuromuscular Training for Knee OA

NANot yet recruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

June 1, 2029

Study Completion Date

January 31, 2030

Conditions
Osteoarthritis of Knee
Interventions
DEVICE

Robot-Aided Off-Axis Neuromuscular Training

A novel custom-designed elliptical trainer is developed, and its footplates are robot-controlled to be moved in four off-axis directions (sliding in/out, pivoting in/out; corresponding to knee valgus/varus, internal rotation/external rotation). Before the training, off-axis neuromechanical assessments will be conducted to determine which specific off-axis direction (valgus, varus, internal rotation, external rotation, or combination of the off-axis directions) has neuromechanical deficits. During the evaluation-based and subject-specific neuromuscular training, the different training modes will be conducted progressively from regular stepping, footplate position control, spring mode, perturbation, to slippery mode.

DEVICE

Traditional elliptical regular stepping

traditional elliptical regular stepping

All Listed Sponsors
lead

University of Maryland, Baltimore

OTHER

NCT07014098 - Robot-Aided Off-Axis Neuromuscular Training for Knee OA | Biotech Hunter | Biotech Hunter