Dynamic Treatment Regimes for Opioid Use Disorder

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

June 1, 2029

Study Completion Date

June 1, 2030

Conditions
Opioid Use Disorder
Interventions
DRUG

Medication for opioid use disorder

A medication treatment component delivered in Week 1 as part of a 2×2 factorial SMART design. The exact content (e.g., treatment modality or intensity) will be finalized based on model results from Aim 1, which identifies optimal dynamic treatment regimes.

BEHAVIORAL

psychotherapy

A behavioral treatment component delivered in Week 1 as part of a 2×2 factorial SMART design. The exact content (e.g., treatment modality or intensity) will be finalized based on model results from Aim 1, which identifies optimal dynamic treatment regimes.

Trial Locations (1)

92612

Discovery Behavioral Health, Irvine

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Brigham and Women's Hospital

OTHER