1,000
Participants
Start Date
May 26, 2021
Primary Completion Date
December 31, 2026
Study Completion Date
March 31, 2027
600 mg Ibuprofen
Treatment patients will receive oral ibuprofen 600 mg three times a day (tid) for up to six weeks. Clinicians in this group may use whatever further analgesia they desire, excluding NSAIDs. For patients who have a clinical concern regarding NSAID and prophylactic anticoagulation, the treating physician may consider prescribing misoprostol.
RECRUITING
Allegheny General Hospital, Pittsburgh
RECRUITING
University of Maryland R Adams Cowley Shock Trauma Center, Baltimore
RECRUITING
Inova Fairfax Hospital, Falls Church
RECRUITING
Vanderbilt Medical Center, Nashville
RECRUITING
University of Mississippi, Jackson
RECRUITING
The MetroHealth System, Cleveland
RECRUITING
Eskenazi Hospital, Indianapolis
RECRUITING
Indiana University-Methodist, Indianapolis
RECRUITING
University of Wisconsin, Madison
RECRUITING
Hennepin Health, Minneapolis
RECRUITING
University of Texas Health Science Center - Houston, Houston
RECRUITING
University of Utah, Salt Lake City
RECRUITING
Harvard Medical Center, Cambridge
RECRUITING
University of Calgary, Foothills Medical Centre, Calgary
United States Department of Defense
FED
Major Extremity Trauma Research Consortium
OTHER