NCT07004764View on ClinicalTrials.gov

Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

December 31, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2027

Conditions
Achilles Tendon Repairs/ReconstructionsPilon Fracture of TibiaTibial Plateau FractureAnkle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar)Calcaneus FracturesTalus FractureWound Infection DeepWound Infection Post-TraumaticWound Dehiscence, Surgical
Interventions
DRUG

Nitroglycerin Ointment 2%

Patients will have pre- and post-nitropaste tissue perfusion measurement with the LA-ICG system.

Trial Locations (2)

21201

The Johns Hopkins Hospital, Baltimore

21224

Johns Hopkins Bayview Medical Center, Baltimore

All Listed Sponsors
collaborator

Orthopaedic Trauma Association

OTHER

lead

Johns Hopkins University

OTHER