Dual-target BCMA-CD19 CAR-T Cell Therapy for RR/MM With Extramedullary Infiltration

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

May 25, 2025

Primary Completion Date

May 25, 2027

Study Completion Date

June 25, 2027

Conditions
Relapsed or Refractory Multiple Myeloma (RRMM)
Interventions
DRUG

Dual-targeting BCMA-CD19 CAR-T cell infusion

Approximately 3-5 days prior to BCMA-CD19 CAR-T cell infusion, subjects are treated with FC regimen (fludarabine and cyclophosphamide) for lymphodepletion. CAR-T cell infusion are performed 48 h after completion of chemotherapy.

All Listed Sponsors
collaborator

Shanghai Liquan Hospital

OTHER

lead

Beijing GoBroad Hospital

OTHER