A Clinical Study of the Interactions Between Azvudine Tablets (FNC) and Rifampicin Capsules (RIF)

PHASE1CompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

December 20, 2021

Primary Completion Date

March 22, 2022

Study Completion Date

October 7, 2023

Conditions
Healthy
Interventions
DRUG

Azvudine tablets(FNC) and Rifampicin Capsules (RIF)

"This study consisted of 3 cycles, each cycle was administered orally for 7 consecutive days, and the washout period between each cycle was 7 days. Subjects were administered the drug as follow:~FNC 3mg (1 tablet)+RIF 600 mg (4 capsules) (taken at the same time), 1 time a day, orally, for 7 consecutive days; RIF: 600 mg (4 capsules) each time, 1 time a day, orally, for 7 consecutive days; FNC: 3 mg (1 tablet) each time, 1 time a day, orally, for 7 consecutive days."

DRUG

Azvudine tablets(FNC) and Rifampicin Capsules (RIF)

"This study consisted of 3 cycles, each cycle was administered orally for 7 consecutive days, and the washout period between each cycle was 10 days. Subjects were administered the drug as follow:~FNC: 3 mg (1 tablet) each time, 1 time a day, orally, for 7 consecutive days; FNC 3mg (1 tablet) +RIF 600 mg (4 capsules) (taken at the same time), 1 time a day, orally, for 7 consecutive days; RIF: 600 mg (4 capsules) each time, 1 time a day, orally, for 7 consecutive days."

DRUG

Azvudine tablets(FNC) and Rifampicin Capsules (RIF)

"This study consisted of 3 cycles, each cycle was administered orally for 7 consecutive days, and the washout period between each cycle was 10 days. Subjects were administered the drug as follow:~RIF: 600 mg (4 capsules), 1 time a day, orally, for 7 consecutive days; FNC: 3 mg (1 tablet) each time, 1 time a day, orally, for 7 consecutive days; FNC 3mg (1 tablet)+RIF 600 mg (4 capsules) (taken at the same time), 1 time a day, orally, for 7 consecutive days."

Trial Locations (1)

Unknown

Heping Hospital Affliliated to Changzhi Medical College, Shanxi

All Listed Sponsors
lead

Henan Genuine Biotech Co., Ltd.

INDUSTRY

NCT07002255 - A Clinical Study of the Interactions Between Azvudine Tablets (FNC) and Rifampicin Capsules (RIF) | Biotech Hunter | Biotech Hunter