Functional Connectivity of the Interoceptive Network in RLS

NARecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

September 16, 2025

Primary Completion Date

October 31, 2026

Study Completion Date

October 31, 2026

Conditions
Restless Legs Syndrome
Interventions
OTHER

Clinical assessment

RLS history, RLS treatments, and International Restless Legs Syndrome Rating Scale (IRLSRS) will be recorded

BEHAVIORAL

auto-questionnaires (PSQI, ISI, ESS and HADS)

To evaluate sleep quality, daytime somnolence and mood disorders (Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), Epworth Sleepiness Scale (ESS) and Hospital Anxiety and Depression Scale (HADS)).

DEVICE

Ecological Momentary Assessment (EMA)

4 electronic interviews administered per day during 14 days by a study-dedicated Android OS smartphone

DEVICE

activity-rest cycle

To further investigate the mutual influence of sleep quality on RLS symptoms and mood, the activity-rest cycle will be monitored by wearable actigraph to be placed on the non-dominant wrist during a period of 13 days and 14 nights.

BEHAVIORAL

auto-questionnaires (ASRS, PSAS, APS, MAIA-2)

Interoceptive awareness and accuracy estimation : Adult ADHD Self-Report Scale (ASRS), Pre-Sleep Arousal Scale (PSAS), Arousal Predisposition Scale (APS) et Multidimensional Assessment of Interoceptive Awareness version 2 (MAIA-2)

DEVICE

MRI

Morning and evening functional brain imaging

Trial Locations (1)

Unknown

RECRUITING

CHU de Bordeaux - Neurophysiologie Clinique de l'Enfant et de l'Adulte, Bordeaux

All Listed Sponsors
collaborator

Restless Legs Syndrome Foundation

UNKNOWN

lead

University Hospital, Bordeaux

OTHER

NCT07001891 - Functional Connectivity of the Interoceptive Network in RLS | Biotech Hunter | Biotech Hunter