Fortifying Healthy Behaviors, Optimizing Medical Therapies and Enhancing Cognitive Function in Older Adults-pilot Study

PHASE2RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

July 31, 2025

Primary Completion Date

May 31, 2026

Study Completion Date

May 31, 2026

Conditions
AgingCognitive DeclineOlder AdultsCardiovascularSedentary BehaviorsImmune SenescenceMotor Function
Interventions
BEHAVIORAL

Risk managment

Behavioral lifestyle changes including an exercise program, healthy eating recommendations, reviewing medical management for cardiometabolic risk conditions, deprescribing review for brain toxic meds, online cognitive training, as well as recommendations to improve sleep quality, or smoking cessation as needed

DRUG

Dasatinib

dasatinib 100mg The intervention will involve the participant taking dasatinib 100mg and quercetin 1250ng combined, intermittenly throughout the trial

DIETARY_SUPPLEMENT

Quercetin (dietary supplement)

e intervention will involve the participant taking dasatinib 100mg and quercetin 1250ng combined, intermittenly throughout the trial

DRUG

Vortioxetine

Participants will be prescribed vortioxetine to take daily, in combination with online cognitive training

Trial Locations (1)

63110

RECRUITING

Washington University School of Medicine, St Louis

All Listed Sponsors
lead

Washington University School of Medicine

OTHER