Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

PHASE2RecruitingINTERVENTIONAL
Enrollment

550

Participants

Timeline

Start Date

September 2, 2025

Primary Completion Date

April 30, 2027

Study Completion Date

May 31, 2027

Conditions
Viral Pneumonia
Interventions
DRUG

SNG001

SNG001 nebuliser solution is presented as a ready-to-use aqueous solution (neutral pH) in glass syringes containing 0.65 mL of drug product solution containing 12 MIU/mL of IFNβ 1a.

DRUG

Placebo

The placebo nebuliser solution is presented in glass syringes containing 0.65 mL of solution containing the same formulation as the study medication but without IFNβ 1a (i.e., only the excipients of the SNG001 solution).

Trial Locations (23)

10016

NOT_YET_RECRUITING

NYU Langone Tisch Hospital, New York

14215

NOT_YET_RECRUITING

VA Western New York Healthcare system, Buffalo

27599

NOT_YET_RECRUITING

University of North Carolina (UNC), Chapel Hill

29621

RECRUITING

AnMed Health Pulmonary and Sleep Medicine, Anderson

30308

NOT_YET_RECRUITING

Emory University, Atlanta

34102

NOT_YET_RECRUITING

NCH Pulmonary Critical Care, Naples

43210

NOT_YET_RECRUITING

The Ohio State University (OSU), Columbus

43608

NOT_YET_RECRUITING

Mercy St. Vincent Medical Center, Toledo

44195

NOT_YET_RECRUITING

The Cleveland Clinic Foundation, Cleveland

45229

NOT_YET_RECRUITING

University of Cincinnati Medical Center (UCMC), Cincinnati

48073

NOT_YET_RECRUITING

William Beaumont Hospital, Royal Oak

48201

NOT_YET_RECRUITING

Wayne State University, Detroit

53226

NOT_YET_RECRUITING

Medical College of Wisconsin, Milwaukee

55905

NOT_YET_RECRUITING

Mayo Clinic - Rochester, Rochester

60611

NOT_YET_RECRUITING

Northwestern University, Chicago

63108

NOT_YET_RECRUITING

Washington University in St. Louis, St Louis

75246

RECRUITING

Baylor University Medical Center, Dallas

77030

NOT_YET_RECRUITING

The University of Texas Health Science Center at Houston, Houston

83404

RECRUITING

Snake River Research, PLLC, Idaho Falls

90502

NOT_YET_RECRUITING

Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical Center, Torrance

95817

NOT_YET_RECRUITING

University of California - Davis, Sacramento

97239-3098

NOT_YET_RECRUITING

Oregon Health & Science University (OHSU), Portland

G4 0SF

RECRUITING

Glasgow Royal Infirmary, Glasgow

All Listed Sponsors
lead

Synairgen Research Ltd.

INDUSTRY

NCT06999603 - Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection | Biotech Hunter | Biotech Hunter