A Single-Center Observational Study on the Impact of Symptom Assessment Timing on the Short-Term Efficacy of 5-ASA Therapy in Patients With Initial-Onset or Relapsed Mild-to-Moderate Active Ulcerative Colitis

Not yet recruitingOBSERVATIONAL
Enrollment

180

Participants

Timeline

Start Date

June 1, 2025

Primary Completion Date

October 31, 2026

Study Completion Date

April 30, 2027

Conditions
Ul
Interventions
DRUG

5-ASA (5-Aminosalicylate)

Specialist doctors decide the administration method of 5-ASA based on the patient's condition (all groups), mainly including topical therapy, or oral therapy (2-4 gram/day).

PROCEDURE

Colon Endoscopy Procedure

Participants in all groups will receive a standard Colon Endoscopy Procedure at 48-week.

DIAGNOSTIC_TEST

Blood Routine Test at 4-week

Participants in will receive a standard Blood Routine Test at 4-week.

DIAGNOSTIC_TEST

Blood Routine Test at 8-week

Participants in will receive a standard Blood Routine Test at 8-week.

DIAGNOSTIC_TEST

Blood Routine Test at 12-week

Participants in will receive a standard Blood Routine Test at 12-week.

DIAGNOSTIC_TEST

Stool Routine Test at 4-week

Participants in will receive a standard Stool Routine Test at 4-week.

DIAGNOSTIC_TEST

Stool Routine Test at 8-week

Participants in will receive a standard Stool Routine Test at 8-week.

DIAGNOSTIC_TEST

Stool Routine Test at 12-week

Participants in will receive a standard Stool Routine Test at 12-week.

DIAGNOSTIC_TEST

Erythrocyte Sedimentation Rate Test at 4-week

Participants in will receive a standard Erythrocyte Sedimentation Rate Test at 4-week.

DIAGNOSTIC_TEST

Erythrocyte Sedimentation Rate Test at 8-week

Participants in will receive a standard Erythrocyte Sedimentation Rate Test at 8-week.

DIAGNOSTIC_TEST

Erythrocyte Sedimentation Rate Test at 12-week

Participants in will receive a standard Erythrocyte Sedimentation Rate Test at 12-week.

DIAGNOSTIC_TEST

C-reactive Protein Test at 4-week

Participants in will receive a standard C-reactive Protein Test at 4-week.

DIAGNOSTIC_TEST

C-reactive Protein Test at 8-week

Participants in will receive a standard C-reactive Protein Test at 8-week.

DIAGNOSTIC_TEST

C-reactive Protein Test at 12-week

Participants in will receive a standard C-reactive Protein Test at 12-week.

DIAGNOSTIC_TEST

Liver Function Test at 4-week

Participants in will receive a standard Liver Function Test at 4-week.

DIAGNOSTIC_TEST

Liver Function Test at 8-week

Participants in will receive a standard Liver Function Test at 8-week.

DIAGNOSTIC_TEST

Liver Function Test at 12-week

Participants in will receive a standard Liver Function Test at 12-week.

DIAGNOSTIC_TEST

Kidney Function Test at 4-week

Participants in will receive a standard Kidney Function Test at 4-week.

DIAGNOSTIC_TEST

Kidney Function Test at 8-week

Participants in will receive a standard Kidney Function Test at 8-week.

DIAGNOSTIC_TEST

Kidney Function Test at 12-week

Participants in will receive a standard Kidney Function Test at 12-week.

Trial Locations (1)

710032

Xijing Hospital of Digestive Diseases, Xi'an

All Listed Sponsors
lead

Xijing Hospital of Digestive Diseases

OTHER

NCT06998693 - A Single-Center Observational Study on the Impact of Symptom Assessment Timing on the Short-Term Efficacy of 5-ASA Therapy in Patients With Initial-Onset or Relapsed Mild-to-Moderate Active Ulcerative Colitis | Biotech Hunter | Biotech Hunter