Evaluating the Influence of Diet-induced Weight Loss on Fat (Adipose) Tissue's Insulin Sensitivity and Testosterone Synthesis in Women With Overweight or Obesity, Insulin Resistance, and Hyperandrogenemia

NAActive, not recruitingINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

January 7, 2024

Primary Completion Date

October 5, 2024

Study Completion Date

April 1, 2026

Conditions
Overweight and ObesityHyperandrogenemiaInsulin Resistance
Interventions
BEHAVIORAL

Mediterranean-based, carbohydrate restricted, calorie reduced diet

Dietary intervention - calorie reduced (300-500 kcal/day below estimated energy needs), carbohydrate restricted (\<100 grams of available carbohydrates per day), Mediterranean-based (high fat diet with an emphasis on the addition of healthy fats - nuts, avocados, olive oil, increasing whole grains, increasing fruit and vegetables, replacing red meats with fish and poultry, reducing dairy, and reducing added sugars) diet.

Trial Locations (1)

65211

University of Missouri, Columbia

All Listed Sponsors
lead

University of Missouri-Columbia

OTHER

NCT06998238 - Evaluating the Influence of Diet-induced Weight Loss on Fat (Adipose) Tissue's Insulin Sensitivity and Testosterone Synthesis in Women With Overweight or Obesity, Insulin Resistance, and Hyperandrogenemia | Biotech Hunter | Biotech Hunter