Communicating Uncertainties Associated With the Benefits and Risks of New Cancer Drugs

NARecruitingINTERVENTIONAL
Enrollment

3,000

Participants

Timeline

Start Date

May 9, 2025

Primary Completion Date

June 30, 2025

Study Completion Date

June 30, 2025

Conditions
Cancer
Interventions
OTHER

Statement communicating uncertainty with a single arm trial

Because Zenova has not been compared to other treatments, it is unknown if Zenova is better, the same, or worse than other treatments for non-small cell lung cancer.

OTHER

Statement communicating uncertainty with limited study duration

Since patients given Zenova were followed for a short time, the longer-term benefits and harms of taking Zenova are unknown.

OTHER

Statement communicating uncertainty with a limited study population

Zenova has not been studied in patients similar to Alex (patients with her race and ethnicity). It is unknown whether Zenova will work and what harms it will have for patients like her.

OTHER

Statement communicating uncertainty with an unvalidated surrogate endpoint

Zenova has only been shown to shrink the size of tumors. It is unknown whether Zenova improves how patients feel or how long they live.

OTHER

Statement communicating uncertainty with treatment effect size

It is unknown whether patients with non-small cell lung cancer will notice an improvement with Zenova.

Trial Locations (1)

02139

RECRUITING

Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston

All Listed Sponsors
collaborator

Harvard Medical School / Harvard Pilgrim Health Care Institute

UNKNOWN

lead

London School of Economics and Political Science

OTHER