ERd Combination Treatment in Newly Diagnosed Multiple Myeloma

PHASE2RecruitingINTERVENTIONAL
Enrollment

104

Participants

Timeline

Start Date

September 16, 2025

Primary Completion Date

September 30, 2030

Study Completion Date

September 30, 2030

Conditions
Multiple Myeloma
Interventions
DRUG

Lenalidomide

Participants will receive 25mg of Lenalidomide orally on Days 2-21 of Cycle 1, then 25 mg by mouth on Days 1-21 of the remaining cycles.

DRUG

Dexamethasone

Participants will receive 20mg of Dexamethasone orally on Days 1, 3, 8, and 15 of Cycle 1, then 4mg orally on Days 1 and 15 of Cycles 4-6.

DRUG

Elranatamab

Participants will receive 12mg Elranatamab subcutaneous (SC) on Cycle 1; 32mg subcutaneous (SC) on Cycle 1 Day 3; 76mg subcutaneous (SC) on Cycle 1 Day 8 and Day 15. Then, participants will receive 76mg subcutaneous (SC) on Days 1 and 15 of Cycles 2-6. Lastly, participants will receive Elranatamab subcutaneous (SC) on Day 1 of the remaining cycles.

Trial Locations (1)

33136

RECRUITING

University of Miami, Miami

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pfizer

INDUSTRY

lead

University of Miami

OTHER

NCT06997081 - ERd Combination Treatment in Newly Diagnosed Multiple Myeloma | Biotech Hunter | Biotech Hunter