SK-NK Injection in Patients With Advanced Solid Tumors Accompanied by Malignant Ascites

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

May 30, 2025

Primary Completion Date

May 30, 2026

Study Completion Date

July 30, 2026

Conditions
Solid Tumor, Malignant Ascites
Interventions
DRUG

SK-NK injection

In this stage, two dose groups are preset, namely 20×108 cells and 30×108 cells. Subjects who meet the inclusion criteria will receive intravenous infusion of SK-NK injection once a week for six consecutive times. After completing six consecutive infusions of SK-NK injection, the researchers evaluated that the patient benefited and could continue to receive six consecutive infusions of SK-NK injection. After completing twelve infusions, the decision on whether to continue the treatment subsequently could be made based on the patient's condition

DRUG

SK-NK injection

Based on the dose selected from the results of the first stage, the clinical efficacy, safety, tolerability and pharmacokinetic characteristics of RP2D were further verified. The types of cancer and the number of cases enrolled in stage II are to be determined

All Listed Sponsors
lead

Tianjin Medical University Cancer Institute and Hospital

OTHER