148
Participants
Start Date
May 31, 2025
Primary Completion Date
July 31, 2026
Study Completion Date
April 30, 2029
Photobiomodulation
Photobiomodulation applications will be performed within 1 hour after the radiotherapy session, covering the entire irradiated area, three times per week, starting from the first day of radiotherapy. The procedure will be conducted using the Antares/IBRAMED® device, with a cluster applicator featuring a 20 cm² contact area and two distinct wavelengths: four infrared laser diodes (808 nm), each with a power of 180 mW, and three red light diodes (630 nm), each with a power of 150 mW. Each diode will deliver 3 J of energy, with the wavelengths applied separately and sequentially.
Sham Control
Group B will have the device in contact with the irradiated area, following the same protocol as Group A, but with the device turned off, receiving no therapeutic light and, therefore, experiencing no biological effects from the light.
National Cancer Institute (INCA-BRAZIL), Rio de Janeiro
National Cancer Institute / Cancer Hospital III - Brazil, Rio de Janeiro
Conselho Nacional de Desenvolvimento Científico e Tecnológico
OTHER_GOV
Instituto Nacional de Cancer, Brazil
OTHER_GOV