Photobiomodulation in Radiodermatitis in People With Breast Cancer

NANot yet recruitingINTERVENTIONAL
Enrollment

148

Participants

Timeline

Start Date

May 31, 2025

Primary Completion Date

July 31, 2026

Study Completion Date

April 30, 2029

Conditions
Breast CancerRadio Dermatitis
Interventions
DEVICE

Photobiomodulation

Photobiomodulation applications will be performed within 1 hour after the radiotherapy session, covering the entire irradiated area, three times per week, starting from the first day of radiotherapy. The procedure will be conducted using the Antares/IBRAMED® device, with a cluster applicator featuring a 20 cm² contact area and two distinct wavelengths: four infrared laser diodes (808 nm), each with a power of 180 mW, and three red light diodes (630 nm), each with a power of 150 mW. Each diode will deliver 3 J of energy, with the wavelengths applied separately and sequentially.

OTHER

Sham Control

Group B will have the device in contact with the irradiated area, following the same protocol as Group A, but with the device turned off, receiving no therapeutic light and, therefore, experiencing no biological effects from the light.

Trial Locations (2)

20560-120

National Cancer Institute (INCA-BRAZIL), Rio de Janeiro

20560-121

National Cancer Institute / Cancer Hospital III - Brazil, Rio de Janeiro

All Listed Sponsors
collaborator

Conselho Nacional de Desenvolvimento Científico e Tecnológico

OTHER_GOV

lead

Instituto Nacional de Cancer, Brazil

OTHER_GOV