140
Participants
Start Date
June 10, 2025
Primary Completion Date
December 31, 2026
Study Completion Date
December 31, 2026
General lifestyle and nutritional education
Participants will receive dietary advice, behavior guidance and nutritional and lifestyle education based on dietary guidelines.
Calorie-restricted balanced diet
Participants will receive dietary advice, behavior guidance and nutritional and lifestyle education by dietitian and physicians. APP-connected wearable devices will be utilized to monitor their dietary intakes and APP-connected scale will be used to monitor their weight changes during interventions.
semaglutide
Participants will receive semaglutide as medically prescribed
Dietary protein supplementation
participants will receive 30 g/day of dietary protein supplementation
Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou
Lead Sponsor
Chinese Academy of Sciences
OTHER_GOV