Probiotic Intervention on Body Weight

NANot yet recruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

June 10, 2025

Primary Completion Date

December 30, 2026

Study Completion Date

December 31, 2026

Conditions
ObesityHomeostasisWeight LossProbiotic Intervention
Interventions
BEHAVIORAL

General lifestyle and nutritional education

Participants will receive dietary advice, behavior guidance and nutritional and lifestyle education based on dietary guidelines.

BEHAVIORAL

Energy-restricted nutritional and lifestyle intervention

Participants will receive dietary advice, behavioral guidance and nutritional and lifestyle education by dietitian and physicians. App-connected wearable devices will be utilized to monitor their dietary intakes and App-connected scale will be used to monitor their weight changes during interventions.

DIETARY_SUPPLEMENT

Placebo

Participants will receive one bag (2 g; 1 × 10¹² CFU) daily of LC-19.

DIETARY_SUPPLEMENT

Probiotic

participants will receive daily one bag of LC-19 (10\^12 cfu/bag).

DRUG

semaglutide

Participants will receive prescibed semaglutide therapy

Trial Locations (1)

310024

Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou

Sponsors
All Listed Sponsors
lead

Chinese Academy of Sciences

OTHER_GOV

NCT06989177 - Probiotic Intervention on Body Weight | Biotech Hunter | Biotech Hunter