A Study to Determine the Recommended Dose and Schedule, and Evaluate the Safety and Preliminary Efficacy of Mezigdomide in Combination With Elranatamab in Participants With Relapsed and/or Refractory Multiple Myeloma

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

62

Participants

Timeline

Start Date

October 7, 2025

Primary Completion Date

May 31, 2027

Study Completion Date

June 3, 2027

Conditions
Multiple Myeloma
Interventions
DRUG

Elranatamab

Specified dose on specified days

DRUG

Mezigdomide

Specified dose on specified days

DRUG

Dexamethasone

Specified dose on specified days

Trial Locations (22)

7030

NOT_YET_RECRUITING

Local Institution - 0017, Trondheim

20246

NOT_YET_RECRUITING

Local Institution - 0013, Hamburg

37007

NOT_YET_RECRUITING

Local Institution - 0022, Salamanca

39008

NOT_YET_RECRUITING

Local Institution - 0021, Santander

77030

RECRUITING

University of Texas MD Anderson Cancer Center, Houston

200434

NOT_YET_RECRUITING

Local Institution - 0031, Shanghai

215006

NOT_YET_RECRUITING

Local Institution - 0030, Suzhou

35294-3300

NOT_YET_RECRUITING

Local Institution - 0001, Birmingham

06510

NOT_YET_RECRUITING

Local Institution - 0029, New Haven

07601

NOT_YET_RECRUITING

Local Institution - 0028, Hackensack

T2N 5G2

NOT_YET_RECRUITING

Local Institution - 0032, Calgary

V5Z 4E6

NOT_YET_RECRUITING

Local Institution - 0026, Vancouver

B3H 2Y9

NOT_YET_RECRUITING

Local Institution - 0027, Halifax

M5G 2M9

RECRUITING

Princess Margaret Cancer Centre, Toronto

01307

NOT_YET_RECRUITING

Local Institution - 0015, Dresden

D-69120

NOT_YET_RECRUITING

Local Institution - 0014, Heidelberg

106 76

NOT_YET_RECRUITING

Local Institution - 0011, Athens

115 28

NOT_YET_RECRUITING

Local Institution - 0012, Athens

0450

NOT_YET_RECRUITING

Local Institution - 0019, Oslo

W1T 7HA

NOT_YET_RECRUITING

Local Institution - 0016, London

SM2 5PT

NOT_YET_RECRUITING

Local Institution - 0018, London

M20 4BX

NOT_YET_RECRUITING

Local Institution - 0020, Manchester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Celgene

INDUSTRY

NCT06988488 - A Study to Determine the Recommended Dose and Schedule, and Evaluate the Safety and Preliminary Efficacy of Mezigdomide in Combination With Elranatamab in Participants With Relapsed and/or Refractory Multiple Myeloma | Biotech Hunter | Biotech Hunter