Efficacy and Safety of a Beet-Derived Inorganic Nitrate-Based Food Product for the Prevention of Contrast-Induced Nephropathy in High-Risk Patients Undergoing Percutaneous Coronary Intervention

NARecruitingINTERVENTIONAL
Enrollment

88

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Contrast-induced Nephropathy Following Percutaneous Intervention (CIN)
Interventions
DIETARY_SUPPLEMENT

Beet-Derived Inorganic Nitrate-Based Food Product

This intervention consists of an orally administered food product enriched with inorganic nitrates derived from beetroot. Participants in the intervention group will consume a standardized dose of 12 mmol of nitrate per day for 5 days (starting 24 hours before PCI and continuing for 4 days post-procedure). The product is designed to enhance nitric oxide bioavailability, improve renal perfusion, reduce oxidative stress, and lower the risk of contrast-induced nephropathy (CIN).

Trial Locations (1)

Unknown

RECRUITING

Federal State Budgetary Institution National Medical Research Center for Therapy and Preventive Medicine of the Ministry of Healthсare of the Russian Federation, Moscow

All Listed Sponsors
lead

National Medical Research Center for Therapy and Preventive Medicine

OTHER_GOV