Clinical Trial of AM80 in Combination With Gemcitabine, Cisplatin, and Nivolumab in Patients With Urothelial Carcinoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

43

Participants

Timeline

Start Date

May 1, 2025

Primary Completion Date

March 1, 2027

Study Completion Date

March 1, 2029

Conditions
Urothelial Carcinoma BladderUrothelial Carcinoma of the Renal Pelvis and UreterUrothelial Carcinoma UrethraUrothelial Carcinoma Recurrent
Interventions
DRUG

Add-on effect of adding tamivarotene (AM80) to gemcitabine, cisplatin, and nivolumab combination therapy

To explore the efficacy and safety of the combination of tamivarotene (AM80), gemcitabine, cisplatin, and nivolumab in the treatment of patients with untreated unresectable or recurrent urothelial cancer

Trial Locations (1)

4668560

RECRUITING

Nagoya University Hospital, Nagoya

All Listed Sponsors
collaborator

Japan Agency for Medical Research and Development

OTHER_GOV

collaborator

Kyushu University

OTHER

collaborator

Chiba University

OTHER

collaborator

University of Tsukuba

OTHER

collaborator

Kyoto University

OTHER

lead

Nagoya University

OTHER