NCT06982222View on ClinicalTrials.gov

Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

December 31, 2025

Primary Completion Date

February 12, 2027

Study Completion Date

February 12, 2027

Conditions
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell CarcinomaMetastatic Malignant Neoplasm in the BoneMetastatic Prostate AdenocarcinomaStage IV Lung Cancer AJCC v8Stage IVB Prostate Cancer AJCC v8
Interventions
PROCEDURE

Biospecimen Collection

Undergo urine and blood sample collection

PROCEDURE

Bone Scan

Undergo technetium TC-99m bone scan

PROCEDURE

Computed Tomography

Undergo PET/CT, SPECT/CT and PSMA PET/CT

PROCEDURE

Positron Emission Tomography

Undergo PET/CT

PROCEDURE

PSMA PET Scan

Undergo PSMA PET/CT

PROCEDURE

Single Photon Emission Computed Tomography

Undergo SPECT/CT

RADIATION

Technetium TC-99m

Undergo technetium TC-99m bone scan

RADIATION

Tin Sn 117m Pentetate

Given IV

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH