A Study Investigating the Safety of RO7795081 and the Effect of RO7795081 on How the Body Processes Pitavastatin and Rosuvastatin in Otherwise Healthy Overweight or Obese Adult Participants

PHASE1RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

June 4, 2025

Primary Completion Date

May 13, 2026

Study Completion Date

May 13, 2026

Conditions
OverweightObesity
Interventions
DRUG

RO7795081

RO7795081 will be administered orally during Periods 3, 4, and 5, according to the protocol.

DRUG

Placebo

Placebo will be administered orally during Periods 3, 4, and 5, according to the protocol.

DRUG

Rosuvastatin

A single 10 mg dose of rosuvastatin (ROS) will be taken on Day 1 of Period 1 and on Day 1 of Period 4.

DRUG

Pitavastatin

A single 1 mg dose of pitavastatin (PIT) will be taken on Day 1 of Period 2 and on Day 1 of Period 5.

Trial Locations (1)

9728 NZ

RECRUITING

ICON Plc (LPRA) - Netherlands, Groningen

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY