Establishment and Effectiveness Evaluation of a Training System for Confocal Laser Endomicroscopy

RecruitingOBSERVATIONAL
Enrollment

147

Participants

Timeline

Start Date

May 31, 2025

Primary Completion Date

July 31, 2025

Study Completion Date

July 31, 2025

Conditions
Gastric CancerGastric High-grade Intraepithelial NeoplasiaGastric Low-grade Intraepithelial NeoplasiaGastritis
Interventions
DIAGNOSTIC_TEST

Probe-based Confocal Laser Endomicroscopy by Experts

Confocal Laser Endomicroscopy (CLE) is an advanced in vivo imaging technique that combines confocal microscopy with endoscopy, enabling real-time, microscopic visualization of tissues at a cellular level during endoscopic procedures. Probe-based CLE (pCLE) can enter the stomach cavity through the biopsy channel of the endoscope and observe the gastric mucosa. To generate diagnostic results of pCLE, two pCLE experts dignosed independent. Any discrepancies are then resolved by a third expert.

DIAGNOSTIC_TEST

magnifying endoscopy with blue laser imaging

Magnifying Endoscopy with Blue Laser Imaging (ME-BLI) is an advanced endoscopic imaging technique that combines high-resolution magnification with laser-enhanced visualization to improve the detection and characterization of gastrointestinal (GI) mucosal lesions. Developed by Fujifilm, BLI utilizes specific laser wavelengths to enhance surface and vascular patterns, making it particularly useful for diagnosing early-stage cancers and precancerous conditions in the stomach, colon, and esophagus. To generate diagnostic results of ME-BLI, two ME-BLI experts dignosed independent. Any discrepancies are then resolved by a third expert.

DIAGNOSTIC_TEST

Probe-based Confocal Laser Endomicroscopy by trainees

Confocal Laser Endomicroscopy (CLE) is an advanced in vivo imaging technique that combines confocal microscopy with endoscopy, enabling real-time, microscopic visualization of tissues at a cellular level during endoscopic procedures. Probe-based CLE (pCLE) can enter the stomach cavity through the biopsy channel of the endoscope and observe the gastric mucosa. The diagnosis results of CLE trainees are generated by each trainee themselves.

Trial Locations (1)

Unknown

RECRUITING

The First Affiliated Hospital of Naval Medical University, Shanghai

All Listed Sponsors
collaborator

China Biotechnology Development Center

UNKNOWN

lead

Changhai Hospital

OTHER

NCT06981819 - Establishment and Effectiveness Evaluation of a Training System for Confocal Laser Endomicroscopy | Biotech Hunter | Biotech Hunter