Performance Study of the Cobas® BV/CV Test on Samples From Participants With and Without Symptoms of Bacterial Vaginosis and Candida Vaginitis

CompletedOBSERVATIONAL
Enrollment

738

Participants

Timeline

Start Date

December 30, 2024

Primary Completion Date

June 30, 2025

Study Completion Date

June 30, 2025

Conditions
Bacterial VaginosisCandida Vaginitis
Interventions
DIAGNOSTIC_TEST

cobas® BV/CV test

The cobas® BV/CV test is an automated, qualitative in vitro real-time PCR diagnostic test that detects bacteria and yeast associated with bacterial vaginosis (BV) and candida vaginitis (CV), respectively. The test does not distinguish among the pathogens but can give an overall qualitative result indicating the presence or absence of pathogen(s) associated with BV and/or CV.

DIAGNOSTIC_TEST

BD Max™ Vaginal Panel

This is an FDA-cleared diagnostic test that will be used as labelled. It will serve as one of three comparators in this study for determining BV patient infection status.

DIAGNOSTIC_TEST

Cepheid Xpert Xpress MVP

This is an FDA-cleared diagnostic test that will be used as labelled. It will serve as one of three comparators in this study for determining BV patient infection status.

DIAGNOSTIC_TEST

Hologic Aptima BV Assay

This is an FDA-cleared diagnostic test that will be used as labelled. It will serve as one of three comparators in this study for determining BV patient infection status.

Trial Locations (10)

1011

Centre Hospitalier Universitaire Vaudois (Chuv), Lausanne

1202

"Diagnostic Consultative Center Ascendent Ltd.", Sofia

27103

Unified Women's Clinical Research/Lyndhurst, Winston-Salem

28562

Eastern Carolina Women's Center, New Bern

33461

Altus Research, Lake Worth

63110

Washington University, St Louis

77023

Planned Parenthood Gulf Coast, Houston

80228

Red Rocks OBGYN, Lakewood

92111

M3 Wake Research - San Diego at Convoy, San Diego

90057-4103

Matrix Clinical Research, Los Angeles

All Listed Sponsors
collaborator

Roche Molecular Systems

UNKNOWN

lead

Hoffmann-La Roche

INDUSTRY

NCT06975436 - Performance Study of the Cobas® BV/CV Test on Samples From Participants With and Without Symptoms of Bacterial Vaginosis and Candida Vaginitis | Biotech Hunter | Biotech Hunter