Human Infection Study of H3N2 Influenza in Healthy Adults

NAActive, not recruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

May 5, 2025

Primary Completion Date

January 30, 2026

Study Completion Date

June 30, 2026

Conditions
Influenza
Interventions
OTHER

A/Texas/71/2017, clade 3C3a H3N2 influenza virus

The intervention product is a live challenge virus that is manufactured in the USA under Good Manufacturing Practice (GMP). The challenge will be administered intranasally using a sprayer device. Participants will be admitted into an inpatient facility prior to the administration of the flu virus. Following inoculation, they will be quarantined for a minimum of 8 days prior to discharge. Participants will receive supportive care and PCR positive participants will receive an effective antiviral medication. Participants will be followed for a total of 6 months.

Trial Locations (1)

3002

Doherty Clinical Trials, Melbourne

All Listed Sponsors
collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

collaborator

WHO Collaborating Centre for Reference and Research on Influenza

UNKNOWN

lead

University of Melbourne

OTHER

NCT06972810 - Human Infection Study of H3N2 Influenza in Healthy Adults | Biotech Hunter | Biotech Hunter