NCT06972576View on ClinicalTrials.gov

Clinical Study of Combined EphA2-targeted CAR-DC and CAR-T Cell Therapy for Non-small Cell Lung Cancer

PHASE1RecruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

May 9, 2025

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2027

Conditions
Non-Small Cell Lung Cancer
Interventions
BIOLOGICAL

EphA2-targeted CAR-T Cells

Autologous T cells genetically modified to express a chimeric antigen receptor (CAR) targeting EphA2

BIOLOGICAL

EphA2-targeted CAR-DCs

Autologous dendritic cells (DCs) genetically modified to express a chimeric antigen receptor (CAR) targeting EphA2

Trial Locations (1)

310009

RECRUITING

Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou

All Listed Sponsors
lead

Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER