Topical Estrogen: Brief Intervention to Improve Postoperative Experience for Transgender Men Undergoing Hysterectomy

PHASE3RecruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

May 1, 2025

Primary Completion Date

September 1, 2026

Study Completion Date

December 1, 2026

Conditions
Postoperative BleedingGender DysphoriaHysterectomy
Interventions
DRUG

Use of topical estradiol

The investigators will conduct a double blinded randomized control pilot trial. Participants will be randomized in 1:1 fashion to either receive no treatment or receive 2g of estradiol cream, placed after clearing the vaginal vault of any blood and discharge, at the conclusion of the surgery.

OTHER

No intervention

This arm will not receive estradiol or other cream

Trial Locations (1)

02905

RECRUITING

Women & Infants Hospital, Providence

All Listed Sponsors
lead

Women and Infants Hospital of Rhode Island

OTHER