Perioperative Blood Conservation: Role of Combined Iron Supplementation Protocols in Reducing Allogeneic Transfusion

NARecruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

May 15, 2025

Primary Completion Date

June 30, 2027

Study Completion Date

September 30, 2027

Conditions
AnemiaIron DeficienciesCardiac Surgery
Interventions
DRUG

Sucrose Iron,subcutaneous recombinant human erythropoietin,intravenous vitamin C

Patients in the experimental group will receive a combination therapy consisting of intravenous sucrose iron (200 mg), subcutaneous recombinant human erythropoietin (150 IU/kg), and intravenous vitamin C (2 g), administered once daily for three consecutive days within the week prior to surgery.

PROCEDURE

Routine perioperative management

Routine perioperative management based on clinical judgment, including observation, monitoring, and standard nursing practices.

Trial Locations (1)

330100

RECRUITING

Department of Anesthesiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou

All Listed Sponsors
collaborator

First Affiliated Hospital of Chongqing Medical University

OTHER

collaborator

Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University

OTHER

collaborator

The First Affiliated Hospital with Nanjing Medical University

OTHER

collaborator

First Affiliated Hospital of Wenzhou Medical University

OTHER

collaborator

Zhejiang Provincial People's Hospital

OTHER

lead

Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER