Exploratory Study on the Treatment of Gout With Potassium Citrate Sustained-release Tablets

PHASE4RecruitingINTERVENTIONAL
Enrollment

312

Participants

Timeline

Start Date

April 10, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

April 30, 2026

Conditions
Hyperuricemia or GoutNephrolithiasis
Interventions
DRUG

Sodium Bicarbonate Oral Capsule

On the basis of the standard uric acid-lowering treatment plan, sodium bicarbonate should be taken three times a day, 1.0g each time

DRUG

Potassium Citrate Tablets

On the basis of the standard uric acid-lowering treatment plan, potassium citrate was taken three times a day, 2.16g each time

DRUG

uric-acid-lowering drug

The control group was treated with the standard uric acid-lowering treatment regimen alone. Uric acid-lowering treatment plan: Maintain the individualized uric acid-lowering treatment plan at the time of patient enrollment. Traditional uric acid-lowering treatment plans include drugs that reduce uric acid production such as febuxostat and allopurinol, and drugs that increase uric acid excretion such as benzbromarone. At the time of enrollment, the uric acid-lowering drugs were stable. The treatment plan for lowering uric acid remained unchanged for 4 weeks after enrollment in the clinical study until the endpoint.

Trial Locations (1)

Unknown

RECRUITING

Huashan hospital, Fudan university, Shanghai

All Listed Sponsors
lead

Huashan Hospital

OTHER