312
Participants
Start Date
April 10, 2024
Primary Completion Date
December 31, 2025
Study Completion Date
April 30, 2026
Sodium Bicarbonate Oral Capsule
On the basis of the standard uric acid-lowering treatment plan, sodium bicarbonate should be taken three times a day, 1.0g each time
Potassium Citrate Tablets
On the basis of the standard uric acid-lowering treatment plan, potassium citrate was taken three times a day, 2.16g each time
uric-acid-lowering drug
The control group was treated with the standard uric acid-lowering treatment regimen alone. Uric acid-lowering treatment plan: Maintain the individualized uric acid-lowering treatment plan at the time of patient enrollment. Traditional uric acid-lowering treatment plans include drugs that reduce uric acid production such as febuxostat and allopurinol, and drugs that increase uric acid excretion such as benzbromarone. At the time of enrollment, the uric acid-lowering drugs were stable. The treatment plan for lowering uric acid remained unchanged for 4 weeks after enrollment in the clinical study until the endpoint.
RECRUITING
Huashan hospital, Fudan university, Shanghai
Huashan Hospital
OTHER