rTMS as Add on Treatment for Substance Use Disorders

NARecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

May 12, 2025

Primary Completion Date

May 31, 2026

Study Completion Date

May 31, 2026

Conditions
Opioid UseAlcohol Use Disorder
Interventions
DEVICE

repetitive transcranial magnetic stimulation (rTMS) for AUD

Transcranial magnetic stimulation (TMS) is a noninvasive form of brain stimulation in which a changing magnetic field is used to cause electric current at a specific area of the brain through electromagnetic induction. To administer TMS, a stimulator equipped with a figure-8 coil will be used. Two separate coils will be used that are similar in appearance and acoustic properties. One active, unblinded, coil will be used to determine resting motor threshold (RMT) and deliver pulses for the recruitment curves; the other coil will be used to deliver rTMS. rTMS stimulation will be targeted using standard EEG electrode locations: FP1 for mPFC and F3 for l-dlPFC.

DEVICE

repetitive transcranial magnetic stimulation (rTMS) for OUD

Description: Transcranial magnetic stimulation (TMS) is a noninvasive form of brain stimulation in which a changing magnetic field is used to cause electric current at a specific area of the brain through electromagnetic induction. To administer TMS, a stimulator equipped with a figure-8 coil will be used. Two separate coils will be used that are similar in appearance and acoustic properties. One active, unblinded, coil will be used to determine resting motor threshold (RMT) and deliver pulses for the recruitment curves; the other coil will be used to deliver rTMS. rTMS stimulation will be targeted using standard EEG electrode location F3 for l-dlPFC.

Trial Locations (1)

06102

RECRUITING

Hartford Healthcare, Hartford

All Listed Sponsors
lead

Yale University

OTHER