Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19

PHASE3RecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

April 18, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2026

Conditions
Long COVID-19
Interventions
DRUG

Low-dose sirolimus

"Participants will take sirolimus, at home, for 12 weeks (3 months).~* 1 pill once a week for 2 weeks (1mg)~* 2 pills once a week for 2 weeks (2mg)~* 4 pills once a week for 8 weeks (4mg)"

DRUG

Placebo

"Participants will take a matching placebo, at home, for 12 weeks (3 months).~* 1 pill once a week for 2 weeks (0mg)~* 2 pills once a week for 2 weeks (0mg)~* 4 pills once a week for 8 weeks (0mg)"

Trial Locations (1)

10029

RECRUITING

Icahn School of Medicine at Mount Sinai, New York

Sponsors
All Listed Sponsors
collaborator

PolyBio Research Foundation

OTHER

collaborator

The Anlyan Center

UNKNOWN

lead

Icahn School of Medicine at Mount Sinai

OTHER