375
Participants
Start Date
August 31, 2025
Primary Completion Date
March 31, 2029
Study Completion Date
August 31, 2029
Mindfulness Meditation
The Mindfulness Meditation trainings will teach participants Shamatha Vipassana, which is the specific form of Mindfulness Meditation typically implemented in mindfulness research. The emphasis is placed upon developing focused attention on an object of awareness, such as the breath. This focus is then expanded to include a more open, non-judgmental monitoring of any sensory, emotional, or cognitive events. Participants will be invited to lie flat on their back (i.e., to mimic conditions in the MRI scanner) and will listen to the clinician read a standardized Mindfulness Meditation script.
Self-Hypnosis
In the Self-Hypnosis group, participants will relax with their eyes closed and, as with Mindfulness Meditation, will lie flat on their lack and will listen to the clinician read a standardized hypnotic script. The Self-Hypnosis practice will include an induction followed by suggestions for decreased pain and improvement in comorbid symptoms (e.g., mood).
The University of Queensland
OTHER
University of Florida
OTHER
University of California, San Diego
OTHER
National Institute on Aging (NIA)
NIH
University of Washington
OTHER