Efficacy of Dextromethorphan-Bupropion Versus SSRIs in the Treatment of Major Depressive Disorder

NAActive, not recruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

May 6, 2025

Primary Completion Date

November 30, 2025

Study Completion Date

December 31, 2025

Conditions
Major Depressive Disorder (MDD)
Interventions
DRUG

Dextromethorphan-Bupropion

Participants will receive a fixed-dose combination of dextromethorphan-bupropion, dosed according to approved guidelines for major depressive disorder, administered orally for 6 weeks.

DRUG

SSRIs

Participants will receive an SSRI at standard therapeutic doses, administered orally for 6 weeks.

Trial Locations (2)

25770

Combined Military Hospital, Nowshera

Department of Psychiatry, Combined Military Hospital Nowshera, Nowshera

All Listed Sponsors
collaborator

CMH Nowshera

UNKNOWN

lead

Asad Ullah Jan

OTHER_GOV

NCT06957223 - Efficacy of Dextromethorphan-Bupropion Versus SSRIs in the Treatment of Major Depressive Disorder | Biotech Hunter | Biotech Hunter