NCT06956300View on ClinicalTrials.gov

TMS for Cognitive Decline in Aging and Preclinical AD

NARecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

April 7, 2025

Primary Completion Date

August 31, 2029

Study Completion Date

August 31, 2029

Conditions
Prodromal Alzheimer's DiseasePreclinical Alzheimer's DiseaseHealthy AgingCognitive Decline
Interventions
DEVICE

Active rTMS

All study participants will receive one block of ACTIVE rTMS. Each block will consist of daily sessions of active rTMS delivered to the left dorsolateral prefrontal cortex over ten days (Monday through Friday).

DEVICE

Sham rTMS

All study participants will receive one block of SHAM rTMS. Each block will consist of daily sessions of SHAM rTMS delivered to the left dorsolateral prefrontal cortex over ten days (Monday through Friday).

Trial Locations (1)

02129

RECRUITING

Massachusetts General Hospital, Boston

All Listed Sponsors
lead

Massachusetts General Hospital

OTHER