NCT06954831View on ClinicalTrials.gov

Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III Breast Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

October 5, 2025

Primary Completion Date

January 31, 2028

Study Completion Date

January 31, 2028

Conditions
Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Breast Carcinoma
Interventions
PROCEDURE

Cone-Beam Computed Tomography

Undergo CBCT

RADIATION

Hypofractionated External Beam Radiation Therapy

Undergo UF-WBI with CB

OTHER

Questionnaire Administration

Ancillary studies

RADIATION

Radiation Boost

Undergo UF-WBI with CB

RADIATION

Whole Breast Irradiation

Undergo UF-WBI with CB

Trial Locations (7)

90503

RECRUITING

City of Hope at South Bay, Torrance

91007

RECRUITING

City of Hope at Arcadia, Arcadia

91010

RECRUITING

City of Hope Medical Center, Duarte

91030

RECRUITING

City of Hope South Pasadena, South Pasadena

91786

RECRUITING

City of Hope Upland, Upland

92618

NOT_YET_RECRUITING

City of Hope at Irvine Lennar, Irvine

93534

RECRUITING

City of Hope Antelope Valley, Lancaster

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

City of Hope Medical Center

OTHER