Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-BEYOND

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

330

Participants

Timeline

Start Date

May 30, 2025

Primary Completion Date

February 28, 2027

Study Completion Date

May 30, 2027

Conditions
Stroke
Interventions
DRUG

Tenecteplase (0.25mg/kg)

Each vial of tenecteplase is reconstituted with 3 ml sterile water for injection and adjusted to a concentration of 5.33 mg/ml. Calculate the total amount of drug according to the subject's actual body weight and measure the required drug volume. The maximum dose should not exceed 25mg. Tenecteplase should be given as a single, intravenous bolus (within 5-10 seconds).

DRUG

Standard medical treatment

Aspirin combined with clopidogrel, aspirin alone, or clopidogrel alone after randomization at the discretion of site researchers according to Chinese Guidelines for Diagnosis and Treatment of Acute Ischemic Stroke 2023.

Trial Locations (1)

100070

Beijing tiantan hospital, Beijing

All Listed Sponsors
lead

Beijing Tiantan Hospital

OTHER