A Study to Assess Adverse Events and Change in Disease Activity of Oral ABBV-453 Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

July 23, 2025

Primary Completion Date

December 31, 2030

Study Completion Date

December 31, 2030

Conditions
Multiple Myeloma
Interventions
DRUG

ABBV-453

Oral Tablet

DRUG

Daratumumab

Subcutaneous (SC) Injection

DRUG

Dexamethasone

Oral Tablet

DRUG

Pomalidomide

Oral Capsule

Trial Locations (16)

2170

RECRUITING

Liverpool Hospital /ID# 272002, Liverpool

2298

RECRUITING

Calvary Mater Newcastle /ID# 272498, Waratah

3065

RECRUITING

St Vincent's Hospital - Melbourne /ID# 271997, Fitzroy

3121

RECRUITING

Epworth Hospital /ID# 272497, Richmond

27514

RECRUITING

University of North Carolina at Chapel Hill /ID# 272454, Chapel Hill

91120

RECRUITING

Hadassah Medical Center-Hebrew University /ID# 271253, Jerusalem

98405

RECRUITING

Northwest Medical Specialties Tacoma /ID# 272506, Tacoma

3525408

RECRUITING

Rambam Health Care Campus /ID# 271256, Haifa

4941492

RECRUITING

Rabin Medical Center /ID# 272073, Petah Tikva

5265601

RECRUITING

The Chaim Sheba Medical Center /ID# 271251, Ramat Gan

6423906

RECRUITING

Tel Aviv Sourasky Medical Center /ID# 271252, Tel Aviv

467-8602

RECRUITING

Nagoya City University Hospital /ID# 271427, Nagoya

602-8566

RECRUITING

University Hospital Kyoto Prefectural University of Medicine /ID# 271911, Kyoto

565-0871

RECRUITING

The University of Osaka Hospital /ID# 271636, Suita-shi

150-8935

RECRUITING

Japanese Red Cross Medical Center /ID# 272018, Shibuya-ku

105-8461

RECRUITING

The Jikei University School of Medicine /ID# 272091, Tokyo

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AbbVie

INDUSTRY