100
Participants
Start Date
September 23, 2025
Primary Completion Date
July 20, 2026
Study Completion Date
August 20, 2026
Inhaled Fentanyl Aerosol
The subjects will be randomly assigned (1:1) to either dosing sequence: in the first cycle, receive an intravenous bolus (5 seconds) of 25μg Fentanyl injection, after at least a 2-week washout period, in the second cycle, receive a single dose of 25μg Fentanyl aerosol inhaler through the Staccato delivery system; or receive the same treatment in the reverse order.
Fentanyl Citrate Injection
The subjects will be randomly assigned (1:1) to either dosing sequence: in the first cycle, receive an intravenous bolus (5 seconds) of 25μg fentanyl injection, after at least a 2-week washout period, in the second cycle, receive a single dose of 25μg fentanyl aerosol inhaler through the Staccato delivery system; or receive the same treatment in the reverse order.
NOT_YET_RECRUITING
Shanghai Sixth People's Hospital, Shanghai
RECRUITING
Henan Tumor Hospital, Zhengzhou
Lead Sponsor
Lee's Pharmaceutical Limited
INDUSTRY