A Trial of MHB088C in Advanced Extrapulmonary Neuroendocrine Cancer

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

May 6, 2025

Primary Completion Date

May 6, 2026

Study Completion Date

May 6, 2028

Conditions
Advanced Extrapulmonary Neuroendocrine Cancer
Interventions
DRUG

MHB088C for Injection (B7-H3 ADC)

MHB088C for Injection, an antibody drug-conjugated molecule (ADC), is conjugated from a humanized monoclonal antibody targeting the B7-H3 molecule and a DNA topoisomerase I inhibitor (TOP1i) via protease-hydrolyzable linkers.The intervention will be administered intravenously at a dose of 2.0 mg/kg every 2 weeks (Q2W) until disease progression, withdrawal from the study, or death.

All Listed Sponsors
lead

Beijing GoBroad Hospital

OTHER