Clinical Investigation of Chemomechanical Parameters for an Efficient Disinfection of the Root Canal

NAActive, not recruitingINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

December 1, 2023

Primary Completion Date

December 12, 2024

Study Completion Date

June 23, 2025

Conditions
Apical PeriodontitisRoot Canal Infection
Interventions
PROCEDURE

Root canal tratment using mecchanical and chemical preparation.

Root canal procedures including access cavity preparation, chemomechanical instrumentation, irrigation with sodium hypoclorite (NaOCl), microbiological sampling and obturation with warm vertical compaction.

DRUG

Sodium Hypochlorite.

Sodium Hypoclorite used as the primary irrigant in the root canal treatment at concentrations of 2.5% (Group A) and 5% (Group B).

DRUG

Hydrogen peroxide.

Applied to the operating field and tooth as part of initial disinfection prior to cavity access.

DRUG

Sodium Sulfate.

Used to inactivate sodium hypoclorite prior to sample collection.

DEVICE

Root ZX mini apex locator (Morita).

Used to determine the working length of the root canal.

DEVICE

Protaper Gold rotary files (Dentslpy Maillefer).

Used for coronal flaring in root canal instrumentation.

DEVICE

Smarttrack and Hyflex totary files.

Used for root canal instrumentation to full working length.

DEVICE

Endo-Eze 27G irrigation needle (Ultradent).

Used to deliver irrigant into the root canal.

Trial Locations (1)

11527

National and Kapodistrian University of Athens, Athens

All Listed Sponsors
lead

National and Kapodistrian University of Athens

OTHER