49
Participants
Start Date
May 6, 2025
Primary Completion Date
October 3, 2025
Study Completion Date
October 3, 2025
AZD5004
"Participants will receive oral tablets of AZD5004 as single dose on the following days, (i) Day 7, Day 14, Day 21, Day 28, Day 35, Day 42 and Day 55 in Part A. (ii) Day 9 to Day15, Day 16, Day 17 to Day 23, Day 24 to Day 30, Day 31 to Day 37, Day 38 to Day 41 and Day 42 in Part B.~(iii) Day 3 to Day 9, Day 10 to Day 25, Day 26 to Day 33, and Day 34 in Part C."
Rosuvastatin
Participants will receive single oral tablets of rosuvastatin 10mg on Days 1, 7, 14, 21, 28, and 35.
Erythromycin
Participants will receive oral doses of erythromycin 500 mg, twice a day from Day 49 to Day 54; and a single dose of 500 mg on Day 55.
Atorvastatin
Participants will receive single oral doses of 40 mg atorvastatin on Days 4, 8, 16, 38, and 42.
Simvastatin
Participants will receive single oral doses of 20 mg simvastatin on Days 1 and 31.
Repaglinide
Participants will receive single oral doses of 0.5 mg repaglinide on Days 1, 10, 26, and 34.
Research Site, Brooklyn
Lead Sponsor
AstraZeneca
INDUSTRY