Photodynamic Diagnosis of Upper Tract Urothelial Carcinoma Using Fluorescence Endoscopy and Oral 5-ALA

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

May 31, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

March 31, 2026

Conditions
Upper Tract Urothelial Carcinoma
Interventions
DRUG

5-Aminolevulinic acid Hydrochloride (Gliolan®)

Participants will receive a single oral dose of 5-aminolevulinic acid (20 mg/kg) approximately 2 to 4 hours prior to surgery. The goal is to evaluate the feasibility of using fluorescence cystoscopy with blue light to improve tumor detection and visualization during ureteroscopic resection of upper tract urothelial carcinoma.

Trial Locations (1)

48202

Henry Ford Hospital, Detroit

All Listed Sponsors
lead

Henry Ford Health System

OTHER