76
Participants
Start Date
April 20, 2025
Primary Completion Date
September 30, 2026
Study Completion Date
December 31, 2027
Paclitaxel + Carboplatin/cisplatin for squamous cell carcinoma and pemetrexed + carboplatin/cisplatin for non-squamous cell carcinoma
"Carboplatin Injection:~One dose of carboplatin AUC 5 IV on Day 1 of each 3-week cycle.~Cisplatin injection:~Cisplatin 75 mg/m2 IV on Day 1 of every 3-week cycle.~Paclitaxel injection:~175 mg/m2 IV on Day 1 of each 3-week cycle.~Pemetrexed Injection:~Pemetrexed 500 mg/m2 IV on Day 1 of each 3-week cycle."
surgery
Subjects with surgical indications will undergo radical surgery for NSCLC,within 4-6 weeks after the last dose of neoadjuvant therapy.
Radiochemotherapy
If radical surgery is not suitable after MDT evaluation, the subjects will receive comprehensive treatment mainly based on radiotherapy.
JS207
JS207 will be administered every 3 weeks for a treatment cycle of 21 days.
Guangdong Provincial People's Hospital, Guangzhou
Shanghai Junshi Bioscience Co., Ltd.
OTHER