A Single-arm, Multicenter Exploratory Clinical Trial of Anlotinib Combined With TQB2450 and the SOX Regimen as First-line Treatment for Advanced Gastric Cancer With Low PD-L1 Expression

PHASE2RecruitingINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

June 7, 2023

Primary Completion Date

June 7, 2025

Study Completion Date

June 1, 2026

Conditions
Advanced Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma
Interventions
DRUG

anlotinib +TQB2450 + Oxaliplatin+S-1

"Anlotinib: 10mg, po, d1-14,q3w,until disease progression or unacceptable toxicity.~TQB2450: 1200mg, iv, d1, q3w,until disease progression or unacceptable toxicity. Oxaliplatin: 130mg/㎡, iv, d1,6 cycles.~S-1:40mg, po, bid, d1\~14,6 cycles."

Trial Locations (1)

Unknown

RECRUITING

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

All Listed Sponsors
lead

Yongxu Jia

OTHER