High-Density EEG-MEG-wearable EEG: Comparison of Quantitative Electroencephalographic Indicators as Neurophysiological Markers of Effectiveness of Mindfulness Therapy in Addition to Standard Treatment in Patients With High-frequency Episodic Migraine

RecruitingOBSERVATIONAL
Enrollment

40

Participants

Timeline

Start Date

April 23, 2024

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
MigraineMigraine DiseaseHigh Frequency Episodic Migraine
Interventions
OTHER

Mindfulness treatment

The Mindfulness treatment will consist of a series of 8 weekly meetings in small groups . An experienced therapist will guide patients and during the sessions they will be encouraged to close their eyes, assume a relaxed posture, focus on breathing and the present moment in order to improve awareness of mental and bodily sensations. Patients will also be encouraged to add a regular, practice at home of about 10 minutes to the group treatment. If necessary, patients in both groups can take the medication they normally take for acute events. These occurrences will be reported in the headache diary given to each subject. Before conducting the study protocol, the investigator will explain the study to each participant and collect a signed copy of the written informed consent. All participants will undergo a clinical, neurophysiological and neuropsychological evaluation before the first session and after the last. In both groups, the usual drug therapies in case of crisis will be allowed.

Trial Locations (1)

20133

RECRUITING

Fondazione IRCCS Istituto Neurologico C. Besta, Milan

All Listed Sponsors
lead

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

OTHER